The author addresses the question of how to use value-learning processes to integrate corporate social responsibility (CSR) in organizations as an interesting challenge in (higher) education. Two strategies have been proposed for the issue of CSR: a compliance strategy and a cultural change strategy (Karssing, 2001). This article focuses on the ethical and philosophical presuppositions of these different approaches. The incorporation of CSR in organizations cannot be accomplished by means of a compliance strategy only. Rather, it needs to be supplemented (...) by a strategy aimed at stimulating a transformation process on the corporate culture level. The perspective of change through dialogue is proposed as a means of innovating the curriculum and the primary processes of student education. This organizational change perspective is demonstrated by describing how (ethical) reflective aspects are integrated in the curriculum of the Free University of Amsterdam. An additional case study on organizational value learning is presented to illustrate the thesis that CSR presupposes that university is an adequate context where life-long learning begins. (shrink)

An able and clear defense of Bradley's principal theses and the underlying conception of metaphysical enterprise. "This is a book about a metaphysician, about metaphysics, and, most importantly, it attempts to develop elements of a metaphysical position long the lines of what is called Absolute Idealism." The Introduction takes up the Verificationists [[sic]] argument and two recent accounts of metaphysics. Part I devotes ten Chapters to the elucidation and defense of Bradley's conception of reality. It culminates in examining three alternative (...) accounts of "Real". Part II considers "the major philosophical theories of the self in order to defend Bradley's Theory of the self within his metaphysical scheme."--A. S. C. (shrink)

This is a critical edition of the work published in 1681, two years after Hobbes' death. The dialogue contains mature reflections of Hobbes on the doctrine of sovereignty. It deals with the relation between law and reason, sovereign power, crimes, heresies and punishments. The editor's introduction sets forth arguments for regarding the text as a complete work, contrary to the views of L. Stephen, Tönnies, and Robertson. A critical analysis of the argument in the dialogue is also provided indicating the (...) relation of the dialogue to Hobbes' political philosophy. The dialogue is interesting in portraying the more "liberal" side of Hobbes. It is an invaluable aid to the study of Hobbes.--A. S. C. (shrink)

An account and development of Arthur Murphy's Theory of Practical Reason and its application to contemporary moral problems. Chapter II gives a schematic account of Murphy's theory of normative discourse. Chapter III contrasts this theory with other theories and approaches. The author justly remarks that "Murphy's intent has been primarily to restore proper balance among considerations that play a role in practical discourse and to steer clear of the pitfalls which would impair or diminish the effectiveness of reason in human (...) actions." Chapter IV deals with "the contemporary erosion of practical reason and critique of existentialistic [[sic]] ethics." Chapter V contains an interesting discussion of Murphy's conception of developing and dynamic self as responsible agent. It gives recognition to the moral self as basic condition that underlies the activity of practical justification. The final chapter undertakes practical applications of the theory expounded. The monograph is a good exposition and defense of Murphy's important contribution to contemporary moral philosophy.--A. S. C. (shrink)

"One basic and underlying assumption of this investigation will be that there is a distinct continuity and development in Berkeley's thought which can be traced through all of his reflective analyses of the problem of perception." The essay argues for Berkeley's theory of perception as a "prototype of the phenomenalists." It argues also for Berkeley's incorporation of elements from the representative theory of perception. Of special interest is the treatment of Berkeley's doctrine of "suggestion" and its connection with the role (...) of imagination in the perception of physical objects. The linguistic aspect of Berkeley's work is minimized. Berkeley's theory of notions receives only a passing reference. The last third of the book is a clear and useful discussion of Berkeley and contemporary phenomenalism. It is suggested, though not shown, that Berkeley has affinity with contemporary phenomenology of perception.--A. S. C. (shrink)

The evolution of internation relationships is studied by means of a mathematical model based on a popular rule of triadic interaction: the friend of my friend is my friend, the friend of my enemy is my enemy, the enemy of my enemy is my friend, the enemy of my friend is my enemy. The rule is shown to lead to the formation and preservation of unipolar and bipolar configurations of nations, with the strengths of relationships, both friendly and conflictual, intensifying (...) through time. These results confirm speculations originally made in static, graph theoretic studies of the balancing of relationships within individuals, small groups and systems of nations. (shrink)

The fourth publication of the monograph series of the Society for Asian and Comparative Philosophy, this lengthy letter of Leibniz on Chinese philosophy is an important contribution to East-West philosophical dialogue, for it depicts a sympathetic yet critical assessment of Chinese philosophy on the basis of translations and secondary sources available to Leibniz. Leibniz’s interest, as the translators point out, was not merely ecumenical, but an expression of high regard for the intrinsic contributions of Chinese thought. In spite of mistakes (...) in chronology, authorship, and interpretation of key notions of Chinese philosophy, Leibniz’s letter is important in the use of philosophical argumentation in the rebuttal of the historical and theological arguments given by Antonio Caballero a Santa Maria and Nicholas Longobardi who opposed the accommodationist position of Matteo Ricci. Leibniz’s letter cannot be regarded as a good guide to Chinese philosophy. But it has a place in the history of East-West philosophy in exemplifying the commendable attitude that combines serious appreciation and critical assessment. The translators have provided an excellent introductory guide to this Discourse. The explanatory notes and comments are quite helpful to the readers. An appendix on "Variant Readings of the Text" and a good bibliography are also provided.—A.S.C. (shrink)

A lucidly written and original contribution to the study of the concept of expression. "The aim has been to construct an analysis from the examination of typical forms of human expressions and from the logical implications of our description of such expressions." An interesting theory emerges from such an analysis in Chapters I and II. The theory is "extended to language in Chapter III and to art in Chapters IV and V." Chapter I deals with behavior and expression and plausibly (...) argues for the thesis that intentionality is characteristic of expressible states of the person and that these expressions are "noncontingently connected with behavioral patterns associated with them." Chapter II takes up the topic of inference. It begins with the distinction between "Ø-expression" and "expression of Ø." The former is claimed to be a "description of certain observable features of a situation;" and the latter is an "inference warranting expression, relating some intentional state of a person to particular aspects of his observable behavior." It is argued that the nature of warrantable inference is non-causal, but "one which moves from a part of a conceptual complex to another part, or to the whole of it." Chapter III contains a good discussion of the distinction between belief and opinion, expressive and performative uses of language. The chapter concludes with the statement that "linguistic expression, like its behavioral counterpart, preserves an inferential connection with intentional states of the person." The last two chapters deal with art as expression. The appendix contains quotations from prominent expression theorists. A useful bibliography is also provided.--A. S. C. (shrink)

A welcome reprint of an important work of Hutcheson with an excellent philosophical and scholarly study of the issues between Hutcheson and the rationalist Gilbert Burnet in respect to the former's contributions to metaethics. The study, modestly entitled "Editor's Introduction" is a philosophical contribution to the study of the Moral Sense Theory which argues forcibly for the plausibility of Hutcheson's epistemology of morals as a form of non-cognitivism that recognizes the proper role of reason. Peach adopts a defeasibility interpretation of (...) Hutcheson's Moral Theory. Unlike the principle of Benevolence, which is a moral principle, "the principle of approval is primarily descriptive and psychological." It is maintained that the vindication of Hutcheson's theory appeals to "the concept of a way of life in which the satisfaction of examined desires is maximized, to the concept of the kind of person, all things considered, one wants to be." Professor Peach's challenging interpretation is worthy of careful study. The appendix reprints the correspondence between Gilbert Burnet and Francis Hutcheson.--A. S. C. (shrink)

The present essay attempts to establish a naturalistic theory for the pursuit of ideals. It is argued that "the necessary condition for the fulfillment of human life" lies in the pursuit of science, morality, and art. After setting forth the view of man as a product of nature with characteristic traits of symbolic response, plasticity of drives, consciousness, and self as a personality, a general chapter is devoted to the discussion of ideals. On this theme, Krikorian expounds a "contextualistic naturalistic" (...) thesis that regards "ideals as natural aspirations that function in a variety of contexts." The crucial question deals with the criteria for evaluating competing ideals. Four criteria are suggested: 1) "firm roots in human nature," 2) universality of scope, 3) personal appeal, and 4) the pragmatic test or "persistence through time." It is not clear how these alleged criteria can yield rational comparative evaluation, since no careful exposition or arguments are offered for the acceptability of these criteria. (shrink)

This is a challenging and original work on the concept of justification and its application to ethical statements. The book divides into two parts. The first part is devoted to a systematic treatment of the nature of justification. It begins with a critical rejection of the deductive model. Wellman presents plausible arguments for the existence of non-deductive evidences in ethics and shows how ethical theories can be tested by "thought-experiment" as analogous to the confirmation of scientific theories by laboratory trials. (...) An interesting kind of inference termed "conductive reasoning" is described. It is argued that this third form of reasoning can be validly used in justifying ethical conclusions. Distinctive of conductive reasoning is its non-formal and inconclusive feature. Its validity is alleged to lie in its dependence upon the content of the argument. But by and large there is no way to judge the validity of these basic ethical arguments but by thinking them through and feeling their logical force." Wellman goes on to develop a challenge-response model for understanding the nature of justification. Justification is "to be understood essentially as a process of responding to challenges made." However, Wellman makes no attempt to consider the role of moral concepts in determining the validity of conductive reasoning and its role in the justification of ethical statements. Part II considers the dimensions of ethical justification in terms of the model of challenge and response. Seven species of challenge are described: truth, truth-value, meaningfulness, validity, validity-value, competence, and knowability. On the whole the book contains challenging views and material for the epistemology of ethics.--A. S. C. (shrink)

Competition among scientists for funding, positions and prestige, among other things, is often seen as a salutary driving force in U.S. science. Its effects on scientists, their work and their relationships are seldom considered. Focus-group discussions with 51 mid- and early-career scientists, on which this study is based, reveal a dark side of competition in science. According to these scientists, competition contributes to strategic game-playing in science, a decline in free and open sharing of information and methods, sabotage of others’ (...) ability to use one’s work, interference with peer-review processes, deformation of relationships, and careless or questionable research conduct. When competition is pervasive, such effects may jeopardize the progress, efficiency and integrity of science. (shrink)

This original and important work is a sequel to Conceptual Idealism and The Primacy of Practice. It is a systematic treatment of the "problem of the legitimation of factual knowledge"-a central issue of rational warrant or cognitive rationality. It offers a doctrine of methodological pragmatism, as distinct from theses pragmatism—a distinction analogous to act- and rule-utilitarianism. Theses pragmatism "asserts that a proposition is to be accepted if its adoption is maximally success-promoting," whereas methodological pragmatism "asserts that a proposition is to (...) be accepted if it conforms to an epistemologically warranted criterion and that a criterion is warranted if its adoption as a generic principle for propositional acceptance is maximally success-promoting ". Thus what is offered is a pragmatic justification of cognitive methodology in factual inquiry rather than the pragmatic validation of factual theses. (shrink)

This is a comprehensive and appreciative account of Dewey’s philosophy of value. It succeeds in rectifying certain current misconceptions of Dewey’s aims and contributions to moral philosophy, and in clearly presenting a coherent theory of value. Gouinlock begins his account by laying stress upon Dewey’s Experience and Nature as a key to Dewey’s thought. Chapter 1 is devoted to this task. It is held that "Dewey develops and articulates an inclusive philosophy by characterizing such things as art, science, and value (...) with a common set of concepts denoting the generic traits of experience." There is also a discussion of Dewey’s philosophic method and the uses and abuses of experience. Chapter 2 deals with man and nature and Dewey’s critical response to bifurcation between mind and body, and the relation between individual and society. Chapter 3 begins with Nature and Value. Here one finds a good discussion of ends-in-view and values. A great stress is laid on Dewey’s use of metaphysical concepts in value analysis, in particular the needed stress on the inclusive unity of means and end. (shrink)

This book is another work on the voluminous literature on the Private Language Argument. The author devotes his arguments solely to a refutation of "anti-private language thesis" as it appears in the articles of N. Malcolm, J. D. Carney, and Newton Garver. Two arguments of the thesis are considered without ascription to Wittgenstein’s Philosophical Investigations. The first is the familiar "The Diary Keeper Argument" found in Wittgenstein : "The claim that the supposition that one could keep a record of a (...) particular kind of sensation having no publicly observable behavioral or circumstantial indicators is unintelligible". Smerud’s attack on this argument in part relies on Ayer’s paper "Can There Be a Private Language?" on the issue of recognition. For the issue on the criterion requirement, Smerud appealed to J. J. Thomson’s paper "Private Languages" as a basis for argument. No note is taken of the criticism of the relevance of verification principle to the issue in D. Locke’s Myself and Others. (shrink)

An excellent collection of lectures. The collection consists of the following: Carl C. Hempel, "On the Structure of Scientific Theories"; W. V. Quine, "Stimulus and Meaning"; Stuart Hampshire, "Aesthetic as the Middle Ground"; H. D. Aiken, "On the Concept of a Moral Principle"; J. O. Urmson, "Utilitarianism"; John Wild, "Is There an Existential A Priori?"; Aron Gurwitsch, "The Husserlian Conception of the Intentionality of Consciousness"; Quentin Lauer, "The Phenomenon of Reason"; and Walter Kaufmann, "The Riddle of Oedipus: Tragedy and Philosophy." (...) These essays represent original contributions to philosophy of science, ethics, and phenomenology and existentialism.--A. S. C. (shrink)

For scholars of American philosophy, this anthology of essays on S. C. Pepper's works on metaphysics, aesthetics, and value theory is especially a welcome one. Also included is a reprint of a little known but valuable essay by Pepper entitled "Metaphor in Philosophy," which originally appeared in volume 3 of Phillip S. Wiener's Dictionary of the History of Ideas. In this essay, Pepper discusses his root metaphor theory in relation to Bacon and Kant, and some contemporary uses of the notion (...) of paradigm, e.g., Wittgenstein and Kuhn. Lewis E. Hahn's "The Stephen C. Pepper Papers, 1903-1972" gives an informative account of six book-length unpublished manuscripts in the Pepper Archives at the Southern Illinois University. The rest of the essays concentrate on the various aspects of Pepper's works. A few deal with aesthetic theory and its application to critical practice. Of philosophical interests are papers by Elmer H. Duncan, David B. Richardson, Robert J. Yanal, Robert L. Armstrong, and Brian Caraher, and a short essay by Charles Hartshorne and a response by Joseph H. Monast. Duncan gives a just but critical account of the neglect of Pepper's Sources of Value, and a highly appreciative appraisal of Pepper's World Hypotheses. Caraher's careful essay on the conflicting root metaphors in Frege's theory of meaning offers interesting application of Pepper's conception of formism and contextualism to problems in Frege's philosophy. A variety of problems such as the root metaphor theory, descriptive definition and aesthetic experience are discussed. Efron's long introductory essay entitled "Pepper's Continuing Value" serves its purpose well in terms of indicating Pepper's influence in non-philosophical disciplines and the problems that arise in Pepper's value theory. What is missed is a sustained critical examination of Pepper's root metaphor theory, characterization of the various world hypotheses including Pepper's own selectivism, and its relation to ethical theory. The anthology however is useful in indicating the scope of Pepper's influence and the need to examine his contributions with reference to contemporary philosophical problems.--A.S.C. (shrink)

This book is an anthology of essays dealing with the problem of the justification of claims to factual knowledge of various sorts. All, except one excerpted from a book, were originally journal articles. Part one, contains essays by R. F. Holland, William Earle, and E. J. Furlong on the problem of memory. Part two, contains essays by A. J. Ayer, C. H. Whiteley, and H. H. Price. Part three contains essays by Ayer, R. J. Hirst, and C. H. Whiteley. A (...) general introduction precedes the essays. A useful bibliographical essay is also given.--A. S. C. (shrink)

This is a sustained attack on what the author termed "decido-phobia"—the fear of making fateful decisions. The book begins with an illuminating discussion of ten popular strategies of decido-phobia. Of particular interest to moral philosophy is the attack on "moral rationalism" which "claims that purely rational procedures can show what one ought to do or what would constitute a just society". "Moral irrationalism" is also criticized for ignoring the relevance of reasons "when one is confronted with fateful decision". An ethics (...) of autonomous men is proposed as an alternative to decido-phobia. This ethics involves four cardinal virtues of love, honesty, courage, and "humbition," the last a new coinage for "fusion of ambition and honesty." Both the concepts of justice and guilt are subjected to detailed criticism, since they constitute the chief obstacles on the road to autonomy. Unlike Kantian autonomy, Professor Kaufmann focuses on that which "consists of making with open eyes the decisions that give shape to one’s life". There is no need of Kantian maxims or categorical imperative. Autonomy involves a new integrity or high standards of honesty which consist in a sort of lived intellectual honesty that is characteristic of a mind that is open to alternatives and spirit of questions. Alienation is regarded as a price of autonomy. A searching critique of current conceptions of alienation is given in Chapter 6. The author recommends a creative autonomous way of life. In his concluding words "guilt is mired in the past, as is retributive justice. Distributive justice is struck in the present, but by the time it has figured out how to cope with that, it is dated. We must move beyond guilt and justice. We must give up the pleasant notion that we can have all good things at once. What is best is not things at all but creative autonomy". This is an important theme and requires closer scrutiny of its central arguments and its suggested alternative ethics of creative autonomy.—A.S.C. (shrink)

The aim "has been to provide the general reader with a reliable and trustworthy account of the life, teaching and influence of Confucius and to show how a man, comparatively insignificant and obscure in his own day, came to occupy a supreme place as the Great and Revered Teacher of the Chinese people." This aim is admirably fulfilled in this sympathetic study of the roots and history of Confucian civilization and its continuing revival of interest, both in the mainland and (...) in areas of Chinese Dispersion, in Taiwan, Singapore, and Hong Kong. Part I gives a good account of the "unique and distinctive place given to Confucius, the founder of one of the world’s greatest systems of religion and philosophical thought." A persuasive case is offered for the defense of the religious dimension of Confucian thought, though its content is essentially ethical. Professor Smith has, in the main, succeeded in conveying the Confucian religious attitude. Part II devotes to a discussion of Confucian civilization from the triumph of Confucianism in the Han Dynasty, and its role until the founding of the Republic of China in 1911. It deals with the development of Neo-Confucian systems and the state cult. A great emphasis is placed on the process that led to the apex of the Confucian civilization in the Manchu Dynasty. The book concludes with an assessment of Confucius: "The great ideals of individual perfection and a harmonious social order which Confucius inculcated are as relevant in the modern world as they were nearly 2500 years ago.... He retains his place, and will still retain his place among the wise ones of the earth who sought after righteousness and found it a thing of great price. Confucius is China’s greatest gift to mankind." The book is a contribution to contemporary reassessment of Confucian thought.—A. S. C. (shrink)

A clearly written book that purports to analyze "the ends men pursue, and the ways in which these ends are ordered in some kind of system." The driving force behind the analysis is the attempt to present ends, or at least some important ends, as complex entities having a discernible and significant structure, and then to present the priorities, preferences, and relationships that men impose on their ends as themselves constituting a complex, coherent structure, whose principles of ordering may be (...) discerned and criticized. Part one deals with the structure and ordering of ends and reflects the influence of Kant and Rawls. Part two deals with rational ends and social structures, and part three with life and death as values. Of great practical interest are certain concepts such as life plan and budget risk in dealing with the problems of life and death. The book repays careful study.--A. S. C. (shrink)

A collection of eight essays, this book is not intended as a comprehensive anthology like K. T. Fann’s Symposium on Austin. G. J. Warnock’s foreword indicates an attempt to rectify the apparent misunderstandings of Austin and his intentions. With the exception of the essays by D. F. Pears and John R. Searle, all are written especially for the volume. Three of the works, those by Sir Isaiah Berlin, George Pitcher, and G. J. Warnock, present an informative account of Austin’s activities (...) at Oxford. Professor Berlin’s "Austin and the Early Beginning of Oxford Philosophy" offers a valuable personal account of Austin’s early years as "a very clear, acute, and original intellect." In the "Thursday meetings", Austin’s main purpose seemed to Berlin "then, and afterwards, to be the establishing of particular truths with a view to generalizing from them, or eliciting principles at a later stage." Pitcher’s "Austin: A Personal Memoir" gives an account of Austin’s stay and influence at Harvard in 1955. Warnock’s "Saturday Mornings" recollects Austin’s activities in the 1950’s. (shrink)

This is a comprehensive investigation of the foundations of value theory. It is a survey of some two or three thousand appraisive concepts in the English language, partly "in order to show that ethics and value theory are but stunted growths if they try to confine their attention merely to the vocabulary of general or ultimate appraisives: good, bad, right, wrong". The book contains three parts. Part I deals with Procedures of Appraisal and Judgment, i.e., with the capacities of the (...) mind to respond or react appetitively or emotionally to the environment. Five topics are examined: enjoyment, response, appraisal, enactment, and moral involvement. (shrink)

The current study verified the association between cognitive process such as attention, executive functioning, and legal capacity in patients with bipolar disorder. The sample consisted of 72 participants, assorted to episodic patients, euthymic patients, and healthy controls. We used the following neuropsychological measures: subtests of the Wechsler Abbreviated Intelligence Scale : vocabulary and matrix reasoning; Continuous Performance Test ; Five Digit Test ; and Rey–Osterrieth Complex Figure. Euthymic patients expressed slower processing speed compared to HC. They tended to make more (...) errors with slightly worse discrimination, suggesting more impulsiveness. On the contrary, episodic patients showed worse discrimination, committed more omissions, were more inconsistent with regard to response speed, showed more difficulties in organizing their actions, and were more rigid. The results suggest that bipolar patients in episode express more cognitive impairments that can compromise the quality of legal capacity. These results highlight the need for more protective support for episodic BD patients regarding legal capacity. (shrink)

This book formulates and defends a form of idealism that shows the influences of Kant, Leibniz, Peirce, and Anglo-American neo-Hegelians. The general position is characterized as conceptual idealism. "It maintains that the concepts we standardly employ in constituting our view of reality—even extramental, material reality-involves an essential reference to minds and their capabilities." Conceptual idealism is distinct from the causal version; it is essentially concerned with the deployment of our present conceptual framework. "A concept is mind-involving in the present, conceptualistic (...) sense if its full and adequate explication—not just on the side of its semantical meaning-content, but also on that of its applicability-conditions—cannot be carried out without reference to those functions which, like thinking, imagining, assuming, etc., are characteristic capabilities of mind.". (shrink)

The rule of rescue describes the powerful human proclivity to rescue identified endangered lives, regardless of cost or risk. Deciding whether or not to perform a decompressive craniectomy as a life-saving or ‘rescue’ procedure for a young person with a severe traumatic brain injury provides a good example of the ethical tensions that occur in these situations. Unfortunately, there comes a point when the primary brain injury is so severe that if the patient survives they are likely to remain severely (...) disabled and fully dependent. The health resource implications of this outcome are significant. By using a web-based outcome prediction model this study compares the long-term outcome and designation of two groups of patients. One group had a very severe injury as adjudged by the model and the other group a less severe injury. At 18 month follow-up there were significant differences in outcome and healthcare requirements. This raises important ethical issues when considering life-saving but non-restorative surgical intervention. The discussion about realistic outcome cannot be dichotomised into simply life or death so that the outcome for the patient must enter the equation. As in other ‘rescue situations’, the utility of the procedure cannot be rationalised on a mere cost–benefit analysis. A compromise has to be reached to determine at what point either the likely outcome would be unacceptable to the person on whom the procedure is being performed or the social utility gained from the rule of rescue intervention fails to justify the utilitarian value and justice of equitable resource allocation. (shrink)

Background Residual dried blood spots (rDBS) from newborn screening programmes represent a valuable resource for medical research, from basic sciences, through clinical to public health. In Hong Kong, there is no legislation for biobanking. Parents’ view on the retention and use of residual newborn blood samples could be cultural-specific and is important to consider for biobanking of rDBS. Objective To study the views and concerns on long-term storage and secondary use of rDBS from newborn screening programmes among Hong Kong Chinese (...) parents. Methods A mixed-method approach was used to study the views and concerns on long-term storage and secondary use of rDBS from newborn screening programmes among Hong Kong Chinese parents of children 0–3 years or expecting parents through focus groups (8 groups; 33 participants) and a survey (n = 1012, 85% mothers) designed with insights obtained from the focus groups. We used framework analysis to summarise the themes as supportive factors, concerns and critical arguments for retention and secondary use of rDBS from focus group discussion. We used multiple logistic regression to assess factors associated with support for retention and secondary use of rDBS in the survey. Results Both in focus groups and survey, majority of parents were not aware of the potential secondary use of rDBS. Overall secondary use of rDBS in medical research was well accepted by a large proportion of Hong Kong parents, even if all potential future research could not be specified in a broad consent. However parents were concerned about potential risks of biobanking rDBS including leaking of data and mis-use of genetic information. Parents wanted to be asked for permission before rDBS are stored and mainly did not accept an “opt-out” approach. The survey showed that parents born in mainland China, compared to Hong Kong born parents, had lower awareness of newborn screening but higher support in biobanking rDBS. Higher education was associated with support in rDBS biobanking only among fathers. Conclusion Long-term storage and secondary use of rDBS from newborn screening for biomedical research and a broad consent for biobanking of rDBS are generally acceptable to Hong Kong parents given their autonomy is respected and their privacy is protected, highlighting the importance of an accountable governance and a transparent access policy for rDBS biobanks. (shrink)

This target article draws together two groups of experimental studies on the control of human movement through peripheral feedback and centrally generated signals of motor commands. First, during natural movement, feedback from muscle, joint, and cutaneous afferents changes; in human subjects these changes have reflex and kinesthetic consequences. Recent psychophysical and microneurographic evidence suggests that joint and even cutaneous afferents may have a proprioceptive role. Second, the role of centrally generated motor commands in the control of normal movements and movements (...) following acute and chronic deafferentation is reviewed. There is increasing evidence that subjects can perceive their motor commands under various conditions, but that this is inadequate for normal movement; deficits in motor performance arise when the reliance on proprioceptive feedback is abolished either experimentally or because of pathology. During natural movement, the CNS appears to have access to functionally useful input from a range of peripheral receptors as well as from internally generated command signals. The unanswered questions that remain suggest a number of avenues for further research. (shrink)